A New Approach for Quantitative Phosphoproteomic Dissection of Signaling Pathways Applied to T Cell Receptor Activation
GO Map
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Molecular Functions
GO | Term | Proteins | |
---|---|---|---|
temp | GO:0005515 | protein binding | 93 |
temp | None | - | 37 |
temp | GO:0044822 | poly(A) RNA binding | 15 |
temp | GO:0042802 | identical protein binding | 13 |
temp | GO:0098641 | cadherin binding involved in cell-cell adhesion | 12 |
temp | GO:0004674 | protein serine/threonine kinase activity | 10 |
temp | GO:0019901 | protein kinase binding | 10 |
temp | GO:0004672 | protein kinase activity | 8 |
temp | GO:0005524 | ATP binding | 8 |
temp | GO:0005102 | receptor binding | 7 |
temp | GO:0004715 | non-membrane spanning protein tyrosine kinase activity | 6 |
temp | GO:0016301 | kinase activity | 6 |
temp | GO:0042803 | protein homodimerization activity | 5 |
temp | GO:0003677 | DNA binding | 4 |
temp | GO:0003723 | RNA binding | 4 |
temp | GO:0004707 | MAP kinase activity | 4 |
temp | GO:0004713 | protein tyrosine kinase activity | 4 |
temp | GO:0005070 | SH3/SH2 adaptor activity | 4 |
temp | GO:0017124 | SH3 domain binding | 4 |
temp | GO:0031625 | ubiquitin protein ligase binding | 4 |
temp | GO:0046982 | protein heterodimerization activity | 4 |
temp | GO:0002020 | protease binding | 3 |
temp | GO:0002039 | p53 binding | 3 |
temp | GO:0003713 | transcription coactivator activity | 3 |
temp | GO:0004435 | phosphatidylinositol phospholipase C activity | 3 |
temp | GO:0004629 | phospholipase C activity | 3 |
temp | GO:0004888 | transmembrane signaling receptor activity | 3 |
temp | GO:0005057 | receptor signaling protein activity | 3 |
temp | GO:0005085 | guanyl-nucleotide exchange factor activity | 3 |
temp | GO:0005088 | Ras guanyl-nucleotide exchange factor activity | 3 |
temp | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding | 3 |
temp | GO:0008270 | zinc ion binding | 3 |
temp | GO:0019899 | enzyme binding | 3 |
temp | GO:0019900 | kinase binding | 3 |
temp | GO:0019904 | protein domain specific binding | 3 |
temp | GO:0048306 | calcium-dependent protein binding | 3 |
temp | GO:0050321 | tau-protein kinase activity | 3 |
temp | GO:0051082 | unfolded protein binding | 3 |
temp | GO:0051087 | chaperone binding | 3 |
temp | GO:0000287 | magnesium ion binding | 2 |
temp | GO:0001085 | RNA polymerase II transcription factor binding | 2 |
temp | GO:0003714 | transcription corepressor activity | 2 |
temp | GO:0003725 | double-stranded RNA binding | 2 |
temp | GO:0003743 | translation initiation factor activity | 2 |
temp | GO:0003779 | actin binding | 2 |
temp | GO:0004459 | L-lactate dehydrogenase activity | 2 |
temp | GO:0004693 | cyclin-dependent protein kinase activity | 2 |
temp | GO:0004725 | protein tyrosine phosphatase activity | 2 |
temp | GO:0004842 | ubiquitin-protein ligase activity | 2 |
temp | GO:0005168 | neurotrophin TRKA receptor binding | 2 |
temp | GO:0005176 | ErbB-2 class receptor binding | 2 |
temp | GO:0005178 | integrin binding | 2 |
temp | GO:0005198 | structural molecule activity | 2 |
temp | GO:0005391 | sodium:potassium-exchanging ATPase activity | 2 |
temp | GO:0005543 | phospholipid binding | 2 |
temp | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding | 2 |
temp | GO:0008013 | beta-catenin binding | 2 |
temp | GO:0008022 | protein C-terminus binding | 2 |
temp | GO:0008134 | transcription factor binding | 2 |
temp | GO:0008237 | metallopeptidase activity | 2 |
temp | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity | 2 |
temp | GO:0019902 | phosphatase binding | 2 |
temp | GO:0023026 | MHC class II protein complex binding | 2 |
temp | GO:0030159 | receptor signaling complex scaffold activity | 2 |
temp | GO:0031072 | heat shock protein binding | 2 |
temp | GO:0034236 | protein kinase A catalytic subunit binding | 2 |
temp | GO:0042169 | SH2 domain binding | 2 |
temp | GO:0042277 | peptide binding | 2 |
temp | GO:0042288 | MHC class I protein binding | 2 |
temp | GO:0042608 | T cell receptor binding | 2 |
temp | GO:0043274 | phospholipase binding | 2 |
temp | GO:0043539 | protein serine/threonine kinase activator activity | 2 |
temp | GO:0044325 | ion channel binding | 2 |
temp | GO:0044548 | S100 protein binding | 2 |
temp | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity | 2 |
temp | GO:0046983 | protein dimerization activity | 2 |
temp | GO:0048365 | Rac GTPase binding | 2 |
temp | GO:0051015 | actin filament binding | 2 |
temp | GO:0051059 | NF-kappaB binding | 2 |
temp | GO:1990239 | steroid hormone binding | 2 |
temp | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | 1 |
temp | GO:0000993 | RNA polymerase II core binding | 1 |
temp | GO:0001106 | RNA polymerase II transcription corepressor activity | 1 |
temp | GO:0001227 | RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription | 1 |
temp | GO:0001671 | ATPase activator activity | 1 |
temp | GO:0001948 | glycoprotein binding | 1 |
temp | GO:0003682 | chromatin binding | 1 |
temp | GO:0003700 | sequence-specific DNA binding transcription factor activity | 1 |
temp | GO:0003712 | transcription cofactor activity | 1 |
temp | GO:0003729 | mRNA binding | 1 |
temp | GO:0003735 | structural constituent of ribosome | 1 |
temp | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity | 1 |
temp | GO:0003878 | ATP citrate synthase activity | 1 |
temp | GO:0003924 | GTPase activity | 1 |
temp | GO:0003993 | acid phosphatase activity | 1 |
temp | GO:0004000 | adenosine deaminase activity | 1 |
temp | GO:0004004 | ATP-dependent RNA helicase activity | 1 |
temp | GO:0004013 | adenosylhomocysteinase activity | 1 |
temp | GO:0004157 | dihydropyrimidinase activity | 1 |
temp | GO:0004177 | aminopeptidase activity | 1 |
temp | GO:0004222 | metalloendopeptidase activity | 1 |
temp | GO:0004402 | histone acetyltransferase activity | 1 |
temp | GO:0004430 | 1-phosphatidylinositol 4-kinase activity | 1 |
temp | GO:0004614 | phosphoglucomutase activity | 1 |
temp | GO:0004619 | phosphoglycerate mutase activity | 1 |
temp | GO:0004634 | phosphopyruvate hydratase activity | 1 |
temp | GO:0004697 | protein kinase C activity | 1 |
temp | GO:0004699 | calcium-independent protein kinase C activity | 1 |
temp | GO:0004702 | receptor signaling protein serine/threonine kinase activity | 1 |
temp | GO:0004708 | MAP kinase kinase activity | 1 |
temp | GO:0004709 | MAP kinase kinase kinase activity | 1 |
temp | GO:0004721 | phosphoprotein phosphatase activity | 1 |
temp | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity | 1 |
temp | GO:0004791 | thioredoxin-disulfide reductase activity | 1 |
temp | GO:0004818 | glutamate-tRNA ligase activity | 1 |
temp | GO:0004827 | proline-tRNA ligase activity | 1 |
temp | GO:0004859 | phospholipase inhibitor activity | 1 |
temp | GO:0004871 | signal transducer activity | 1 |
temp | GO:0004872 | receptor activity | 1 |
temp | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity | 1 |
temp | GO:0005003 | ephrin receptor activity | 1 |
temp | GO:0005004 | GPI-linked ephrin receptor activity | 1 |
temp | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity | 1 |
temp | GO:0005080 | protein kinase C binding | 1 |
temp | GO:0005083 | small GTPase regulator activity | 1 |
temp | GO:0005089 | Rho guanyl-nucleotide exchange factor activity | 1 |
temp | GO:0005093 | Rab GDP-dissociation inhibitor activity | 1 |
temp | GO:0005096 | GTPase activator activity | 1 |
temp | GO:0005100 | Rho GTPase activator activity | 1 |
temp | GO:0005109 | frizzled binding | 1 |
temp | GO:0005137 | interleukin-5 receptor binding | 1 |
temp | GO:0005158 | insulin receptor binding | 1 |
temp | GO:0005200 | structural constituent of cytoskeleton | 1 |
temp | GO:0005509 | calcium ion binding | 1 |
temp | GO:0005518 | collagen binding | 1 |
temp | GO:0005525 | GTP binding | 1 |
temp | GO:0005544 | calcium-dependent phospholipid binding | 1 |
temp | GO:0008017 | microtubule binding | 1 |
temp | GO:0008047 | enzyme activator activity | 1 |
temp | GO:0008093 | cytoskeletal adaptor activity | 1 |
temp | GO:0008320 | protein transmembrane transporter activity | 1 |
temp | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity | 1 |
temp | GO:0008607 | phosphorylase kinase regulator activity | 1 |
temp | GO:0010484 | H3 histone acetyltransferase activity | 1 |
temp | GO:0010485 | H4 histone acetyltransferase activity | 1 |
temp | GO:0015276 | ligand-gated ion channel activity | 1 |
temp | GO:0016303 | 1-phosphatidylinositol-3-kinase activity | 1 |
temp | GO:0017016 | Ras GTPase binding | 1 |
temp | GO:0017022 | myosin binding | 1 |
temp | GO:0017048 | Rho GTPase binding | 1 |
temp | GO:0017137 | Rab GTPase binding | 1 |
temp | GO:0019003 | GDP binding | 1 |
temp | GO:0019834 | phospholipase A2 inhibitor activity | 1 |
temp | GO:0019887 | protein kinase regulator activity | 1 |
temp | GO:0019903 | protein phosphatase binding | 1 |
temp | GO:0030235 | nitric-oxide synthase regulator activity | 1 |
temp | GO:0030332 | cyclin binding | 1 |
temp | GO:0030506 | ankyrin binding | 1 |
temp | GO:0030544 | Hsp70 protein binding | 1 |
temp | GO:0030546 | receptor activator activity | 1 |
temp | GO:0030549 | acetylcholine receptor activator activity | 1 |
temp | GO:0030554 | adenyl nucleotide binding | 1 |
temp | GO:0030619 | U1 snRNA binding | 1 |
temp | GO:0030676 | Rac guanyl-nucleotide exchange factor activity | 1 |
temp | GO:0030695 | GTPase regulator activity | 1 |
temp | GO:0030742 | GTP-dependent protein binding | 1 |
temp | GO:0030911 | TPR domain binding | 1 |
temp | GO:0030955 | potassium ion binding | 1 |
temp | GO:0031402 | sodium ion binding | 1 |
temp | GO:0031432 | titin binding | 1 |
temp | GO:0031996 | thioesterase binding | 1 |
temp | GO:0031997 | N-terminal myristoylation domain binding | 1 |
temp | GO:0032266 | phosphatidylinositol-3-phosphate binding | 1 |
temp | GO:0032403 | protein complex binding | 1 |
temp | GO:0035173 | histone kinase activity | 1 |
temp | GO:0035575 | histone demethylase activity (H4-K20 specific) | 1 |
temp | GO:0035613 | RNA stem-loop binding | 1 |
temp | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding | 1 |
temp | GO:0042393 | histone binding | 1 |
temp | GO:0042623 | ATPase activity, coupled | 1 |
temp | GO:0042826 | histone deacetylase binding | 1 |
temp | GO:0043125 | ErbB-3 class receptor binding | 1 |
temp | GO:0043130 | ubiquitin binding | 1 |
temp | GO:0043236 | laminin binding | 1 |
temp | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding | 1 |
temp | GO:0043560 | insulin receptor substrate binding | 1 |
temp | GO:0043621 | protein self-association | 1 |
temp | GO:0044183 | protein binding involved in protein folding | 1 |
temp | GO:0045545 | syndecan binding | 1 |
temp | GO:0046538 | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity | 1 |
temp | GO:0046790 | virion binding | 1 |
temp | GO:0046875 | ephrin receptor binding | 1 |
temp | GO:0047485 | protein N-terminus binding | 1 |
temp | GO:0048156 | tau protein binding | 1 |
temp | GO:0050681 | androgen receptor binding | 1 |
temp | GO:0051020 | GTPase binding | 1 |
temp | GO:0051117 | ATPase binding | 1 |
temp | GO:0051287 | NAD binding | 1 |
temp | GO:0051525 | NFAT protein binding | 1 |
temp | GO:0070006 | metalloaminopeptidase activity | 1 |
temp | GO:0070300 | phosphatidic acid binding | 1 |
temp | GO:0070851 | growth factor receptor binding | 1 |
temp | GO:0070883 | pre-miRNA binding | 1 |
temp | GO:0072542 | protein phosphatase activator activity | 1 |
temp | GO:0090631 | pre-miRNA transporter activity | 1 |
temp | GO:0097472 | cyclin-dependent protein kinase activity | 1 |
temp | GO:0098604 | adenosylselenohomocysteinase activity | 1 |
temp | GO:0098625 | methylselenol reductase activity | 1 |
temp | GO:0098626 | methylseleninic acid reductase activity | 1 |
temp | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway | 1 |
temp | GO:1990226 | histone methyltransferase binding | 1 |
Cellular Components
GO | Term | Proteins | |
---|---|---|---|
GO:0005829 | cytosol | 69 | |
GO:0005737 | cytoplasm | 59 | |
GO:0005886 | plasma membrane | 49 | |
GO:0070062 | extracellular vesicular exosome | 49 | |
GO:0005634 | nucleus | 44 | |
None | - | 34 | |
GO:0005654 | nucleoplasm | 30 | |
GO:0016020 | membrane | 28 | |
GO:0005730 | nucleolus | 16 | |
GO:0005913 | cell-cell adherens junction | 12 | |
GO:0005925 | focal adhesion | 11 | |
GO:0005887 | integral to plasma membrane | 8 | |
GO:0042101 | T cell receptor complex | 8 | |
GO:0005813 | centrosome | 7 | |
GO:0005856 | cytoskeleton | 7 | |
GO:0045121 | membrane raft | 7 | |
GO:0005615 | extracellular space | 6 | |
GO:0005739 | mitochondrion | 6 | |
GO:0005794 | Golgi apparatus | 6 | |
GO:0005874 | microtubule | 6 | |
GO:0016021 | integral to membrane | 6 | |
GO:0031012 | extracellular matrix | 6 | |
GO:0031982 | vesicle | 6 | |
GO:0005576 | extracellular region | 5 | |
GO:0005768 | endosome | 5 | |
GO:0005769 | early endosome | 5 | |
GO:0009986 | cell surface | 5 | |
GO:0015629 | actin cytoskeleton | 5 | |
GO:0015630 | microtubule cytoskeleton | 5 | |
GO:0030054 | cell junction | 5 | |
GO:0031234 | extrinsic to internal side of plasma membrane | 5 | |
GO:0005911 | cell-cell junction | 4 | |
GO:0016607 | nuclear speck | 4 | |
GO:0030496 | midbody | 4 | |
GO:0043231 | intracellular membrane-bounded organelle | 4 | |
GO:0043234 | protein complex | 4 | |
GO:1903561 | extracellular vesicle | 4 | |
GO:0001726 | ruffle | 3 | |
GO:0005622 | intracellular | 3 | |
GO:0005770 | late endosome | 3 | |
GO:0005783 | endoplasmic reticulum | 3 | |
GO:0008180 | signalosome | 3 | |
GO:0030027 | lamellipodium | 3 | |
GO:0072686 | mitotic spindle | 3 | |
GO:0000784 | nuclear chromosome, telomeric region | 2 | |
GO:0000786 | nucleosome | 2 | |
GO:0000788 | nuclear nucleosome | 2 | |
GO:0001772 | immunological synapse | 2 | |
GO:0005635 | nuclear envelope | 2 | |
GO:0005681 | spliceosomal complex | 2 | |
GO:0005764 | lysosome | 2 | |
GO:0005765 | lysosomal membrane | 2 | |
GO:0005819 | spindle | 2 | |
GO:0005852 | eukaryotic translation initiation factor 3 complex | 2 | |
GO:0005876 | spindle microtubule | 2 | |
GO:0005890 | sodium:potassium-exchanging ATPase complex | 2 | |
GO:0005901 | caveola | 2 | |
GO:0005923 | tight junction | 2 | |
GO:0009897 | external side of plasma membrane | 2 | |
GO:0014069 | postsynaptic density | 2 | |
GO:0016323 | basolateral plasma membrane | 2 | |
GO:0016604 | nuclear body | 2 | |
GO:0030425 | dendrite | 2 | |
GO:0030529 | ribonucleoprotein complex | 2 | |
GO:0030877 | beta-catenin destruction complex | 2 | |
GO:0033565 | ESCRT-0 complex | 2 | |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 2 | |
GO:0042383 | sarcolemma | 2 | |
GO:0042995 | cell projection | 2 | |
GO:0043005 | neuron projection | 2 | |
GO:0048471 | perinuclear region of cytoplasm | 2 | |
GO:1990909 | Wnt signalosome | 2 | |
GO:0000123 | histone acetyltransferase complex | 1 | |
GO:0000139 | Golgi membrane | 1 | |
GO:0000228 | nuclear chromosome | 1 | |
GO:0000243 | commitment complex | 1 | |
GO:0000307 | cyclin-dependent protein kinase holoenzyme complex | 1 | |
GO:0000785 | chromatin | 1 | |
GO:0000813 | ESCRT I complex | 1 | |
GO:0000922 | spindle pole | 1 | |
GO:0001650 | fibrillar center | 1 | |
GO:0002102 | podosome | 1 | |
GO:0005604 | basement membrane | 1 | |
GO:0005641 | nuclear envelope lumen | 1 | |
GO:0005643 | nuclear pore | 1 | |
GO:0005685 | U1 snRNP | 1 | |
GO:0005759 | mitochondrial matrix | 1 | |
GO:0005771 | multivesicular body | 1 | |
GO:0005798 | Golgi-associated vesicle | 1 | |
GO:0005801 | cis-Golgi network | 1 | |
GO:0005811 | lipid particle | 1 | |
GO:0005814 | centriole | 1 | |
GO:0005832 | chaperonin-containing T-complex | 1 | |
GO:0005845 | mRNA cap binding complex | 1 | |
GO:0005895 | interleukin-5 receptor complex | 1 | |
GO:0005912 | adherens junction | 1 | |
GO:0008023 | transcription elongation factor complex | 1 | |
GO:0009346 | citrate lyase complex | 1 | |
GO:0009898 | internal side of plasma membrane | 1 | |
GO:0009925 | basal plasma membrane | 1 | |
GO:0010008 | endosome membrane | 1 | |
GO:0016235 | aggresome | 1 | |
GO:0016324 | apical plasma membrane | 1 | |
GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex | 1 | |
GO:0019034 | viral replication complex | 1 | |
GO:0022625 | cytosolic large ribosomal subunit | 1 | |
GO:0030017 | sarcomere | 1 | |
GO:0030056 | hemidesmosome | 1 | |
GO:0030118 | clathrin coat | 1 | |
GO:0030133 | transport vesicle | 1 | |
GO:0030139 | endocytic vesicle | 1 | |
GO:0030315 | T-tubule | 1 | |
GO:0030424 | axon | 1 | |
GO:0030426 | growth cone | 1 | |
GO:0030659 | cytoplasmic vesicle membrane | 1 | |
GO:0030660 | Golgi-associated vesicle membrane | 1 | |
GO:0030669 | clathrin-coated endocytic vesicle membrane | 1 | |
GO:0030864 | cortical actin cytoskeleton | 1 | |
GO:0031092 | platelet alpha granule membrane | 1 | |
GO:0031209 | SCAR complex | 1 | |
GO:0031233 | intrinsic to external side of plasma membrane | 1 | |
GO:0031463 | Cul3-RING ubiquitin ligase complex | 1 | |
GO:0031594 | neuromuscular junction | 1 | |
GO:0031902 | late endosome membrane | 1 | |
GO:0031905 | early endosome lumen | 1 | |
GO:0031965 | nuclear membrane | 1 | |
GO:0031985 | Golgi cisterna | 1 | |
GO:0032045 | guanyl-nucleotide exchange factor complex | 1 | |
GO:0032587 | ruffle membrane | 1 | |
GO:0033269 | internode region of axon | 1 | |
GO:0033588 | Elongator holoenzyme complex | 1 | |
GO:0034704 | calcium channel complex | 1 | |
GO:0034751 | aryl hydrocarbon receptor complex | 1 | |
GO:0036064 | cilium basal body | 1 | |
GO:0042105 | alpha-beta T cell receptor complex | 1 | |
GO:0042565 | RNA nuclear export complex | 1 | |
GO:0042581 | specific granule | 1 | |
GO:0042582 | azurophil granule | 1 | |
GO:0042643 | actomyosin, actin part | 1 | |
GO:0043025 | neuronal cell body | 1 | |
GO:0043195 | terminal button | 1 | |
GO:0043235 | receptor complex | 1 | |
GO:0044297 | cell body | 1 | |
GO:0044445 | cytosolic part | 1 | |
GO:0045111 | intermediate filament cytoskeleton | 1 | |
GO:0045202 | synapse | 1 | |
GO:0045335 | phagocytic vesicle | 1 | |
GO:0055037 | recycling endosome | 1 | |
GO:0071004 | U2-type prespliceosome | 1 | |
GO:0071011 | precatalytic spliceosome | 1 | |
GO:0072562 | blood microparticle | 1 | |
GO:0090543 | Flemming body | 1 | |
GO:0097452 | GAIT complex | 1 | |
GO:0099617 | matrix side of mitochondrial inner membrane | 1 | |
GO:1990667 | PCSK9-AnxA2 complex | 1 |
Biological Processes
GO | Term | Proteins | |
---|---|---|---|
None | - | 39 | |
GO:0045087 | innate immune response | 25 | |
GO:0007165 | signal transduction | 24 | |
GO:0050852 | T cell receptor signaling pathway | 16 | |
GO:0007596 | blood coagulation | 15 | |
GO:0044281 | small molecule metabolic process | 15 | |
GO:0006468 | protein phosphorylation | 14 | |
GO:0007173 | epidermal growth factor receptor signaling pathway | 14 | |
GO:0007411 | axon guidance | 14 | |
GO:0035556 | intracellular signal transduction | 14 | |
GO:0038095 | Fc-epsilon receptor signaling pathway | 14 | |
GO:0048011 | nerve growth factor receptor signaling pathway | 14 | |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 13 | |
GO:0007264 | small GTPase mediated signal transduction | 11 | |
GO:0008543 | fibroblast growth factor receptor signaling pathway | 11 | |
GO:0030168 | platelet activation | 11 | |
GO:0048010 | vascular endothelial growth factor receptor signaling pathway | 11 | |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 10 | |
GO:0010467 | gene expression | 10 | |
GO:0000186 | activation of MAPKK activity | 8 | |
GO:0016477 | cell migration | 8 | |
GO:0018105 | peptidyl-serine phosphorylation | 8 | |
GO:0042110 | T cell activation | 8 | |
GO:0000165 | MAPK cascade | 7 | |
GO:0007265 | Ras protein signal transduction | 7 | |
GO:0016032 | viral reproduction | 7 | |
GO:0019221 | cytokine-mediated signaling pathway | 7 | |
GO:0031295 | T cell costimulation | 7 | |
GO:0048015 | phosphatidylinositol-mediated signaling | 7 | |
GO:0000278 | mitotic cell cycle | 6 | |
GO:0006461 | protein complex assembly | 6 | |
GO:0006915 | apoptotic process | 6 | |
GO:0006955 | immune response | 6 | |
GO:0006996 | organelle organization | 6 | |
GO:0007166 | cell surface receptor signaling pathway | 6 | |
GO:0007243 | intracellular protein kinase cascade | 6 | |
GO:0018107 | peptidyl-threonine phosphorylation | 6 | |
GO:0038083 | peptidyl-tyrosine autophosphorylation | 6 | |
GO:0050776 | regulation of immune response | 6 | |
GO:0007202 | activation of phospholipase C activity | 5 | |
GO:0007268 | synaptic transmission | 5 | |
GO:0008286 | insulin receptor signaling pathway | 5 | |
GO:0018108 | peptidyl-tyrosine phosphorylation | 5 | |
GO:0034134 | toll-like receptor 2 signaling pathway | 5 | |
GO:0034142 | toll-like receptor 4 signaling pathway | 5 | |
GO:0034162 | toll-like receptor 9 signaling pathway | 5 | |
GO:0034605 | cellular response to heat | 5 | |
GO:0043066 | negative regulation of apoptotic process | 5 | |
GO:0043547 | positive regulation of GTPase activity | 5 | |
GO:0044267 | cellular protein metabolic process | 5 | |
GO:0046777 | protein autophosphorylation | 5 | |
GO:0050853 | B cell receptor signaling pathway | 5 | |
GO:0050900 | leukocyte migration | 5 | |
GO:0051403 | stress-activated MAPK cascade | 5 | |
GO:0061024 | membrane organization | 5 | |
GO:1900034 | regulation of cellular response to heat | 5 | |
GO:0000086 | G2/M transition of mitotic cell cycle | 4 | |
GO:0000187 | activation of MAPK activity | 4 | |
GO:0002223 | stimulatory C-type lectin receptor signaling pathway | 4 | |
GO:0002224 | toll-like receptor signaling pathway | 4 | |
GO:0002250 | adaptive immune response | 4 | |
GO:0002576 | platelet degranulation | 4 | |
GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | 4 | |
GO:0002756 | MyD88-independent toll-like receptor signaling pathway | 4 | |
GO:0005975 | carbohydrate metabolic process | 4 | |
GO:0006006 | glucose metabolic process | 4 | |
GO:0006096 | glycolysis | 4 | |
GO:0006413 | translational initiation | 4 | |
GO:0006928 | cellular component movement | 4 | |
GO:0008063 | Toll signaling pathway | 4 | |
GO:0010628 | positive regulation of gene expression | 4 | |
GO:0014066 | regulation of phosphatidylinositol 3-kinase cascade | 4 | |
GO:0030154 | cell differentiation | 4 | |
GO:0032092 | positive regulation of protein binding | 4 | |
GO:0034130 | toll-like receptor 1 signaling pathway | 4 | |
GO:0034138 | toll-like receptor 3 signaling pathway | 4 | |
GO:0034146 | toll-like receptor 5 signaling pathway | 4 | |
GO:0034166 | toll-like receptor 10 signaling pathway | 4 | |
GO:0035666 | TRIF-dependent toll-like receptor signaling pathway | 4 | |
GO:0038123 | toll-like receptor TLR1:TLR2 signaling pathway | 4 | |
GO:0038124 | toll-like receptor TLR6:TLR2 signaling pathway | 4 | |
GO:0042127 | regulation of cell proliferation | 4 | |
GO:0042981 | regulation of apoptotic process | 4 | |
GO:0043647 | inositol phosphate metabolic process | 4 | |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 4 | |
GO:0048013 | ephrin receptor signaling pathway | 4 | |
GO:0050690 | regulation of defense response to virus by virus | 4 | |
GO:0000398 | mRNA splicing, via spliceosome | 3 | |
GO:0006094 | gluconeogenesis | 3 | |
GO:0006357 | regulation of transcription from RNA polymerase II promoter | 3 | |
GO:0006457 | protein folding | 3 | |
GO:0006914 | autophagy | 3 | |
GO:0006950 | response to stress | 3 | |
GO:0007155 | cell adhesion | 3 | |
GO:0007179 | transforming growth factor beta receptor signaling pathway | 3 | |
GO:0007229 | integrin-mediated signaling pathway | 3 | |
GO:0007346 | regulation of mitotic cell cycle | 3 | |
GO:0007623 | circadian rhythm | 3 | |
GO:0008284 | positive regulation of cell proliferation | 3 | |
GO:0008380 | RNA splicing | 3 | |
GO:0009405 | pathogenesis | 3 | |
GO:0016044 | cellular membrane organization | 3 | |
GO:0016055 | Wnt receptor signaling pathway | 3 | |
GO:0016197 | endosomal transport | 3 | |
GO:0016310 | phosphorylation | 3 | |
GO:0019058 | viral infectious cycle | 3 | |
GO:0019722 | calcium-mediated signaling | 3 | |
GO:0030036 | actin cytoskeleton organization | 3 | |
GO:0030217 | T cell differentiation | 3 | |
GO:0032091 | negative regulation of protein binding | 3 | |
GO:0032212 | positive regulation of telomere maintenance via telomerase | 3 | |
GO:0032886 | regulation of microtubule-based process | 3 | |
GO:0032956 | regulation of actin cytoskeleton organization | 3 | |
GO:0033630 | positive regulation of cell adhesion mediated by integrin | 3 | |
GO:0036258 | multivesicular body assembly | 3 | |
GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway | 3 | |
GO:0042113 | B cell activation | 3 | |
GO:0043161 | proteasomal ubiquitin-dependent protein catabolic process | 3 | |
GO:0043306 | positive regulation of mast cell degranulation | 3 | |
GO:0043536 | positive regulation of blood vessel endothelial cell migration | 3 | |
GO:0044255 | cellular lipid metabolic process | 3 | |
GO:0045059 | positive thymic T cell selection | 3 | |
GO:0050821 | protein stabilization | 3 | |
GO:0051056 | regulation of small GTPase mediated signal transduction | 3 | |
GO:0051084 | 'de novo' posttranslational protein folding | 3 | |
GO:0051090 | regulation of sequence-specific DNA binding transcription factor activity | 3 | |
GO:0051592 | response to calcium ion | 3 | |
GO:0055085 | transmembrane transport | 3 | |
GO:0060333 | interferon-gamma-mediated signaling pathway | 3 | |
GO:0090090 | negative regulation of canonical Wnt receptor signaling pathway | 3 | |
GO:1903543 | positive regulation of exosomal secretion | 3 | |
GO:0000902 | cell morphogenesis | 2 | |
GO:0001666 | response to hypoxia | 2 | |
GO:0001764 | neuron migration | 2 | |
GO:0001837 | epithelial to mesenchymal transition | 2 | |
GO:0001887 | selenium compound metabolic process | 2 | |
GO:0001934 | positive regulation of protein phosphorylation | 2 | |
GO:0001954 | positive regulation of cell-matrix adhesion | 2 | |
GO:0002091 | negative regulation of receptor internalization | 2 | |
GO:0002281 | macrophage activation involved in immune response | 2 | |
GO:0002283 | neutrophil activation involved in immune response | 2 | |
GO:0005977 | glycogen metabolic process | 2 | |
GO:0005980 | glycogen catabolic process | 2 | |
GO:0006090 | pyruvate metabolic process | 2 | |
GO:0006281 | DNA repair | 2 | |
GO:0006325 | chromatin organization | 2 | |
GO:0006334 | nucleosome assembly | 2 | |
GO:0006396 | RNA processing | 2 | |
GO:0006606 | protein import into nucleus | 2 | |
GO:0006612 | protein targeting to membrane | 2 | |
GO:0006661 | phosphatidylinositol biosynthetic process | 2 | |
GO:0006883 | cellular sodium ion homeostasis | 2 | |
GO:0006909 | phagocytosis | 2 | |
GO:0006917 | induction of apoptosis | 2 | |
GO:0006935 | chemotaxis | 2 | |
GO:0006954 | inflammatory response | 2 | |
GO:0006983 | ER overload response | 2 | |
GO:0007005 | mitochondrion organization | 2 | |
GO:0007010 | cytoskeleton organization | 2 | |
GO:0007030 | Golgi organization | 2 | |
GO:0007067 | mitosis | 2 | |
GO:0007163 | establishment or maintenance of cell polarity | 2 | |
GO:0007186 | G-protein coupled receptor signaling pathway | 2 | |
GO:0007212 | dopamine receptor signaling pathway | 2 | |
GO:0007267 | cell-cell signaling | 2 | |
GO:0007399 | nervous system development | 2 | |
GO:0007417 | central nervous system development | 2 | |
GO:0007605 | sensory perception of sound | 2 | |
GO:0010107 | potassium ion import | 2 | |
GO:0010468 | regulation of gene expression | 2 | |
GO:0010634 | positive regulation of epithelial cell migration | 2 | |
GO:0010800 | positive regulation of peptidyl-threonine phosphorylation | 2 | |
GO:0010801 | negative regulation of peptidyl-threonine phosphorylation | 2 | |
GO:0010822 | positive regulation of mitochondrion organization | 2 | |
GO:0010831 | positive regulation of myotube differentiation | 2 | |
GO:0010976 | positive regulation of neuron projection development | 2 | |
GO:0015991 | ATP hydrolysis coupled proton transport | 2 | |
GO:0016070 | RNA metabolic process | 2 | |
GO:0016071 | mRNA metabolic process | 2 | |
GO:0016601 | Rac protein signal transduction | 2 | |
GO:0021762 | substantia nigra development | 2 | |
GO:0021766 | hippocampus development | 2 | |
GO:0030007 | cellular potassium ion homeostasis | 2 | |
GO:0030198 | extracellular matrix organization | 2 | |
GO:0030316 | osteoclast differentiation | 2 | |
GO:0030335 | positive regulation of cell migration | 2 | |
GO:0030511 | positive regulation of transforming growth factor beta receptor signaling pathway | 2 | |
GO:0030855 | epithelial cell differentiation | 2 | |
GO:0031047 | gene silencing by RNA | 2 | |
GO:0031281 | positive regulation of cyclase activity | 2 | |
GO:0031333 | negative regulation of protein complex assembly | 2 | |
GO:0031334 | positive regulation of protein complex assembly | 2 | |
GO:0032435 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process | 2 | |
GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | 2 | |
GO:0032516 | positive regulation of phosphoprotein phosphatase activity | 2 | |
GO:0032740 | positive regulation of interleukin-17 production | 2 | |
GO:0032872 | regulation of stress-activated MAPK cascade | 2 | |
GO:0034220 | ion transmembrane transport | 2 | |
GO:0035307 | positive regulation of protein dephosphorylation | 2 | |
GO:0035335 | peptidyl-tyrosine dephosphorylation | 2 | |
GO:0036016 | cellular response to interleukin-3 | 2 | |
GO:0036376 | sodium ion export from cell | 2 | |
GO:0038066 | p38MAPK cascade | 2 | |
GO:0038127 | ERBB signaling pathway | 2 | |
GO:0042267 | natural killer cell mediated cytotoxicity | 2 | |
GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process | 2 | |
GO:0043065 | positive regulation of apoptotic process | 2 | |
GO:0043087 | regulation of GTPase activity | 2 | |
GO:0043405 | regulation of MAP kinase activity | 2 | |
GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator | 2 | |
GO:0044237 | cellular metabolic process | 2 | |
GO:0045579 | positive regulation of B cell differentiation | 2 | |
GO:0045582 | positive regulation of T cell differentiation | 2 | |
GO:0045663 | positive regulation of myoblast differentiation | 2 | |
GO:0045719 | negative regulation of glycogen biosynthetic process | 2 | |
GO:0045732 | positive regulation of protein catabolic process | 2 | |
GO:0045766 | positive regulation of angiogenesis | 2 | |
GO:0045892 | negative regulation of transcription, DNA-dependent | 2 | |
GO:0045893 | positive regulation of transcription, DNA-dependent | 2 | |
GO:0046641 | positive regulation of alpha-beta T cell proliferation | 2 | |
GO:0046827 | positive regulation of protein export from nucleus | 2 | |
GO:0048675 | axon extension | 2 | |
GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | 2 | |
GO:0051092 | positive regulation of NF-kappaB transcription factor activity | 2 | |
GO:0051281 | positive regulation of release of sequestered calcium ion into cytosol | 2 | |
GO:0051290 | protein heterotetramerization | 2 | |
GO:0051493 | regulation of cytoskeleton organization | 2 | |
GO:0051534 | negative regulation of NFAT protein import into nucleus | 2 | |
GO:0051973 | positive regulation of telomerase activity | 2 | |
GO:0055086 | nucleobase-containing small molecule metabolic process | 2 | |
GO:0060070 | canonical Wnt receptor signaling pathway | 2 | |
GO:0060397 | JAK-STAT cascade involved in growth hormone signaling pathway | 2 | |
GO:0061621 | canonical glycolysis | 2 | |
GO:0070489 | T cell aggregation | 2 | |
GO:0070849 | response to epidermal growth factor stimulus | 2 | |
GO:0071109 | superior temporal gyrus development | 2 | |
GO:0071222 | cellular response to lipopolysaccharide | 2 | |
GO:0071356 | cellular response to tumor necrosis factor | 2 | |
GO:0071364 | cellular response to epidermal growth factor stimulus | 2 | |
GO:0071383 | cellular response to steroid hormone stimulus | 2 | |
GO:0071902 | positive regulation of protein serine/threonine kinase activity | 2 | |
GO:0072540 | T-helper 17 cell lineage commitment | 2 | |
GO:0072584 | caveolin-mediated endocytosis | 2 | |
GO:0072678 | T cell migration | 2 | |
GO:0075733 | intracellular transport of viral material | 2 | |
GO:0086064 | cell communication by electrical coupling involved in cardiac conduction | 2 | |
GO:0090170 | regulation of Golgi inheritance | 2 | |
GO:0090263 | positive regulation of canonical Wnt receptor signaling pathway | 2 | |
GO:0090330 | regulation of platelet aggregation | 2 | |
GO:0097192 | extrinsic apoptotic signaling pathway in absence of ligand | 2 | |
GO:0099565 | chemical synaptic transmission, postsynaptic | 2 | |
GO:1900181 | negative regulation of protein localization to nucleus | 2 | |
GO:1901030 | positive regulation of mitochondrial outer membrane permeabilization | 2 | |
GO:1901216 | positive regulation of neuron death | 2 | |
GO:1901741 | positive regulation of myoblast fusion | 2 | |
GO:1901796 | regulation of signal transduction by p53 class mediator | 2 | |
GO:1902186 | regulation of viral release from host cell | 2 | |
GO:1903416 | response to glycoside | 2 | |
GO:1903779 | regulation of cardiac conduction | 2 | |
GO:1904339 | negative regulation of dopaminergic neuron differentiation | 2 | |
GO:1904355 | positive regulation of telomere capping | 2 | |
GO:1904885 | beta-catenin destruction complex assembly | 2 | |
GO:1904886 | beta-catenin destruction complex disassembly | 2 | |
GO:2000077 | negative regulation of type B pancreatic cell development | 2 | |
GO:2000466 | negative regulation of glycogen (starch) synthase activity | 2 | |
GO:2000641 | regulation of early endosome to late endosome transport | 2 | |
GO:0000055 | ribosomal large subunit export from nucleus | 1 | |
GO:0000056 | ribosomal small subunit export from nucleus | 1 | |
GO:0000060 | protein import into nucleus, translocation | 1 | |
GO:0000075 | cell cycle checkpoint | 1 | |
GO:0000082 | G1/S transition of mitotic cell cycle | 1 | |
GO:0000083 | regulation of transcription involved in G1/S phase of mitotic cell cycle | 1 | |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 1 | |
GO:0000183 | chromatin silencing at rDNA | 1 | |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 1 | |
GO:0000188 | inactivation of MAPK activity | 1 | |
GO:0000209 | protein polyubiquitination | 1 | |
GO:0000226 | microtubule cytoskeleton organization | 1 | |
GO:0000301 | retrograde transport, vesicle recycling within Golgi | 1 | |
GO:0000302 | response to reactive oxygen species | 1 | |
GO:0000305 | response to oxygen radical | 1 | |
GO:0000723 | telomere maintenance | 1 | |
GO:0001501 | skeletal system development | 1 | |
GO:0001525 | angiogenesis | 1 | |
GO:0001765 | membrane raft assembly | 1 | |
GO:0001816 | cytokine production | 1 | |
GO:0001865 | NK T cell differentiation | 1 | |
GO:0001890 | placenta development | 1 | |
GO:0001921 | positive regulation of receptor recycling | 1 | |
GO:0002027 | regulation of heart rate | 1 | |
GO:0002028 | regulation of sodium ion transport | 1 | |
GO:0002098 | tRNA wobble uridine modification | 1 | |
GO:0002183 | cytoplasmic translational initiation | 1 | |
GO:0002227 | innate immune response in mucosa | 1 | |
GO:0002439 | chronic inflammatory response to antigenic stimulus | 1 | |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 1 | |
GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent | 1 | |
GO:0002625 | regulation of T cell antigen processing and presentation | 1 | |
GO:0003197 | endocardial cushion development | 1 | |
GO:0005513 | detection of calcium ion | 1 | |
GO:0005978 | glycogen biosynthetic process | 1 | |
GO:0006085 | acetyl-CoA biosynthetic process | 1 | |
GO:0006101 | citrate metabolic process | 1 | |
GO:0006107 | oxaloacetate metabolic process | 1 | |
GO:0006110 | regulation of glycolysis | 1 | |
GO:0006112 | energy reserve metabolic process | 1 | |
GO:0006139 | nucleobase-containing compound metabolic process | 1 | |
GO:0006144 | purine nucleobase metabolic process | 1 | |
GO:0006154 | adenosine catabolic process | 1 | |
GO:0006259 | DNA metabolic process | 1 | |
GO:0006260 | DNA replication | 1 | |
GO:0006303 | double-strand break repair via nonhomologous end joining | 1 | |
GO:0006335 | DNA replication-dependent nucleosome assembly | 1 | |
GO:0006336 | DNA replication-independent nucleosome assembly | 1 | |
GO:0006351 | transcription, DNA-dependent | 1 | |
GO:0006355 | regulation of transcription, DNA-dependent | 1 | |
GO:0006360 | transcription from RNA polymerase I promoter | 1 | |
GO:0006361 | transcription initiation from RNA polymerase I promoter | 1 | |
GO:0006364 | rRNA processing | 1 | |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 1 | |
GO:0006368 | transcription elongation from RNA polymerase II promoter | 1 | |
GO:0006397 | mRNA processing | 1 | |
GO:0006405 | RNA export from nucleus | 1 | |
GO:0006409 | tRNA export from nucleus | 1 | |
GO:0006412 | translation | 1 | |
GO:0006414 | translational elongation | 1 | |
GO:0006415 | translational termination | 1 | |
GO:0006418 | tRNA aminoacylation for protein translation | 1 | |
GO:0006424 | glutamyl-tRNA aminoacylation | 1 | |
GO:0006433 | prolyl-tRNA aminoacylation | 1 | |
GO:0006458 | 'de novo' protein folding | 1 | |
GO:0006508 | proteolysis | 1 | |
GO:0006509 | membrane protein ectodomain proteolysis | 1 | |
GO:0006513 | protein monoubiquitination | 1 | |
GO:0006607 | NLS-bearing substrate import into nucleus | 1 | |
GO:0006611 | protein export from nucleus | 1 | |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 1 | |
GO:0006622 | protein targeting to lysosome | 1 | |
GO:0006633 | fatty acid biosynthetic process | 1 | |
GO:0006644 | phospholipid metabolic process | 1 | |
GO:0006695 | cholesterol biosynthetic process | 1 | |
GO:0006816 | calcium ion transport | 1 | |
GO:0006886 | intracellular protein transport | 1 | |
GO:0006892 | post-Golgi vesicle-mediated transport | 1 | |
GO:0006897 | endocytosis | 1 | |
GO:0006898 | receptor-mediated endocytosis | 1 | |
GO:0006900 | membrane budding | 1 | |
GO:0006911 | phagocytosis, engulfment | 1 | |
GO:0006921 | cellular component disassembly involved in execution phase of apoptosis | 1 | |
GO:0006930 | substrate-dependent cell migration, cell extension | 1 | |
GO:0006936 | muscle contraction | 1 | |
GO:0006952 | defense response | 1 | |
GO:0006968 | cellular defense response | 1 | |
GO:0006975 | DNA damage induced protein phosphorylation | 1 | |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 1 | |
GO:0006986 | response to unfolded protein | 1 | |
GO:0007015 | actin filament organization | 1 | |
GO:0007016 | cytoskeletal anchoring at plasma membrane | 1 | |
GO:0007017 | microtubule-based process | 1 | |
GO:0007026 | negative regulation of microtubule depolymerization | 1 | |
GO:0007049 | cell cycle | 1 | |
GO:0007052 | mitotic spindle organization | 1 | |
GO:0007059 | chromosome segregation | 1 | |
GO:0007077 | mitotic nuclear envelope disassembly | 1 | |
GO:0007098 | centrosome cycle | 1 | |
GO:0007109 | cytokinesis, completion of separation | 1 | |
GO:0007160 | cell-matrix adhesion | 1 | |
GO:0007162 | negative regulation of cell adhesion | 1 | |
GO:0007172 | signal complex assembly | 1 | |
GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway | 1 | |
GO:0007223 | Wnt receptor signaling pathway, calcium modulating pathway | 1 | |
GO:0007254 | JNK cascade | 1 | |
GO:0007344 | pronuclear fusion | 1 | |
GO:0007409 | axonogenesis | 1 | |
GO:0007413 | axonal fasciculation | 1 | |
GO:0007416 | synapse assembly | 1 | |
GO:0007420 | brain development | 1 | |
GO:0007507 | heart development | 1 | |
GO:0007565 | female pregnancy | 1 | |
GO:0007584 | response to nutrient | 1 | |
GO:0007603 | phototransduction, visible light | 1 | |
GO:0007612 | learning | 1 | |
GO:0007631 | feeding behavior | 1 | |
GO:0008037 | cell recognition | 1 | |
GO:0008045 | motor neuron axon guidance | 1 | |
GO:0008064 | regulation of actin polymerization or depolymerization | 1 | |
GO:0008152 | metabolic process | 1 | |
GO:0008154 | actin polymerization or depolymerization | 1 | |
GO:0008217 | regulation of blood pressure | 1 | |
GO:0008283 | cell proliferation | 1 | |
GO:0008285 | negative regulation of cell proliferation | 1 | |
GO:0008356 | asymmetric cell division | 1 | |
GO:0008360 | regulation of cell shape | 1 | |
GO:0008544 | epidermis development | 1 | |
GO:0008610 | lipid biosynthetic process | 1 | |
GO:0008631 | intrinsic apoptotic signaling pathway in response to oxidative stress | 1 | |
GO:0009615 | response to virus | 1 | |
GO:0009749 | response to glucose stimulus | 1 | |
GO:0009790 | embryo development | 1 | |
GO:0009967 | positive regulation of signal transduction | 1 | |
GO:0009987 | cellular process | 1 | |
GO:0010033 | response to organic substance | 1 | |
GO:0010042 | response to manganese ion | 1 | |
GO:0010324 | membrane invagination | 1 | |
GO:0010469 | regulation of receptor activity | 1 | |
GO:0010501 | RNA secondary structure unwinding | 1 | |
GO:0010543 | regulation of platelet activation | 1 | |
GO:0010629 | negative regulation of gene expression | 1 | |
GO:0010717 | regulation of epithelial to mesenchymal transition | 1 | |
GO:0010718 | positive regulation of epithelial to mesenchymal transition | 1 | |
GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation | 1 | |
GO:0010880 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | 1 | |
GO:0010881 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion | 1 | |
GO:0010977 | negative regulation of neuron projection development | 1 | |
GO:0012501 | programmed cell death | 1 | |
GO:0014038 | regulation of Schwann cell differentiation | 1 | |
GO:0014068 | positive regulation of phosphatidylinositol 3-kinase cascade | 1 | |
GO:0015031 | protein transport | 1 | |
GO:0015936 | coenzyme A metabolic process | 1 | |
GO:0015949 | nucleobase-containing small molecule interconversion | 1 | |
GO:0016049 | cell growth | 1 | |
GO:0016056 | rhodopsin mediated signaling pathway | 1 | |
GO:0016064 | immunoglobulin mediated immune response | 1 | |
GO:0016079 | synaptic vesicle exocytosis | 1 | |
GO:0016233 | telomere capping | 1 | |
GO:0016241 | regulation of macroautophagy | 1 | |
GO:0016572 | histone phosphorylation | 1 | |
GO:0016573 | histone acetylation | 1 | |
GO:0017148 | negative regulation of translation | 1 | |
GO:0019062 | viral attachment to host cell | 1 | |
GO:0019068 | virion assembly | 1 | |
GO:0019082 | viral protein processing | 1 | |
GO:0019083 | viral transcription | 1 | |
GO:0019388 | galactose catabolic process | 1 | |
GO:0019432 | triglyceride biosynthetic process | 1 | |
GO:0019510 | S-adenosylhomocysteine catabolic process | 1 | |
GO:0019731 | antibacterial humoral response | 1 | |
GO:0019985 | translesion synthesis | 1 | |
GO:0021955 | central nervous system neuron axonogenesis | 1 | |
GO:0022011 | myelination in peripheral nervous system | 1 | |
GO:0022400 | regulation of rhodopsin mediated signaling pathway | 1 | |
GO:0022617 | extracellular matrix disassembly | 1 | |
GO:0023014 | signal transduction by phosphorylation | 1 | |
GO:0023021 | termination of signal transduction | 1 | |
GO:0030032 | lamellipodium assembly | 1 | |
GO:0030033 | microvillus assembly | 1 | |
GO:0030182 | neuron differentiation | 1 | |
GO:0030183 | B cell differentiation | 1 | |
GO:0030216 | keratinocyte differentiation | 1 | |
GO:0030307 | positive regulation of cell growth | 1 | |
GO:0030334 | regulation of cell migration | 1 | |
GO:0030509 | BMP signaling pathway | 1 | |
GO:0030521 | androgen receptor signaling pathway | 1 | |
GO:0030574 | collagen catabolic process | 1 | |
GO:0030705 | cytoskeleton-dependent intracellular transport | 1 | |
GO:0030801 | positive regulation of cyclic nucleotide metabolic process | 1 | |
GO:0030834 | regulation of actin filament depolymerization | 1 | |
GO:0030836 | positive regulation of actin filament depolymerization | 1 | |
GO:0030837 | negative regulation of actin filament polymerization | 1 | |
GO:0030879 | mammary gland development | 1 | |
GO:0030950 | establishment or maintenance of actin cytoskeleton polarity | 1 | |
GO:0031098 | stress-activated protein kinase signaling cascade | 1 | |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 1 | |
GO:0031175 | neuron projection development | 1 | |
GO:0031325 | positive regulation of cellular metabolic process | 1 | |
GO:0031340 | positive regulation of vesicle fusion | 1 | |
GO:0031396 | regulation of protein ubiquitination | 1 | |
GO:0031398 | positive regulation of protein ubiquitination | 1 | |
GO:0031529 | ruffle organization | 1 | |
GO:0031643 | positive regulation of myelination | 1 | |
GO:0031647 | regulation of protein stability | 1 | |
GO:0031668 | cellular response to extracellular stimulus | 1 | |
GO:0031954 | positive regulation of protein autophosphorylation | 1 | |
GO:0032079 | positive regulation of endodeoxyribonuclease activity | 1 | |
GO:0032088 | negative regulation of NF-kappaB transcription factor activity | 1 | |
GO:0032147 | activation of protein kinase activity | 1 | |
GO:0032200 | telomere organization | 1 | |
GO:0032261 | purine nucleotide salvage | 1 | |
GO:0032319 | regulation of Rho GTPase activity | 1 | |
GO:0032321 | positive regulation of Rho GTPase activity | 1 | |
GO:0032465 | regulation of cytokinesis | 1 | |
GO:0032480 | negative regulation of type I interferon production | 1 | |
GO:0032495 | response to muramyl dipeptide | 1 | |
GO:0032496 | response to lipopolysaccharide | 1 | |
GO:0032729 | positive regulation of interferon-gamma production | 1 | |
GO:0032755 | positive regulation of interleukin-6 production | 1 | |
GO:0032760 | positive regulation of tumor necrosis factor production | 1 | |
GO:0032776 | DNA methylation on cytosine | 1 | |
GO:0032781 | positive regulation of ATPase activity | 1 | |
GO:0032804 | negative regulation of low-density lipoprotein particle receptor catabolic process | 1 | |
GO:0032855 | positive regulation of Rac GTPase activity | 1 | |
GO:0032930 | positive regulation of superoxide anion generation | 1 | |
GO:0033129 | positive regulation of histone phosphorylation | 1 | |
GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 1 | |
GO:0033353 | S-adenosylmethionine cycle | 1 | |
GO:0033627 | cell adhesion mediated by integrin | 1 | |
GO:0033628 | regulation of cell adhesion mediated by integrin | 1 | |
GO:0033631 | cell-cell adhesion mediated by integrin | 1 | |
GO:0033632 | regulation of cell-cell adhesion mediated by integrin | 1 | |
GO:0034080 | CENP-A containing nucleosome assembly at centromere | 1 | |
GO:0034122 | negative regulation of toll-like receptor signaling pathway | 1 | |
GO:0034123 | positive regulation of toll-like receptor signaling pathway | 1 | |
GO:0034154 | toll-like receptor 7 signaling pathway | 1 | |
GO:0034241 | positive regulation of macrophage fusion | 1 | |
GO:0034329 | cell junction assembly | 1 | |
GO:0034351 | negative regulation of glial cell apoptotic process | 1 | |
GO:0034501 | protein localization to kinetochore | 1 | |
GO:0034612 | response to tumor necrosis factor | 1 | |
GO:0035023 | regulation of Rho protein signal transduction | 1 | |
GO:0035066 | positive regulation of histone acetylation | 1 | |
GO:0035281 | pre-miRNA export from nucleus | 1 | |
GO:0035329 | hippo signaling cascade | 1 | |
GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process | 1 | |
GO:0035372 | protein localization to microtubule | 1 | |
GO:0035574 | histone H4-K20 demethylation | 1 | |
GO:0035924 | cellular response to vascular endothelial growth factor stimulus | 1 | |
GO:0036035 | osteoclast development | 1 | |
GO:0036302 | atrioventricular canal development | 1 | |
GO:0036503 | ERAD pathway | 1 | |
GO:0038128 | ERBB2 signaling pathway | 1 | |
GO:0039694 | viral RNA genome replication | 1 | |
GO:0039702 | viral budding via host ESCRT complex | 1 | |
GO:0040011 | locomotion | 1 | |
GO:0040029 | regulation of gene expression, epigenetic | 1 | |
GO:0042102 | positive regulation of T cell proliferation | 1 | |
GO:0042117 | monocyte activation | 1 | |
GO:0042119 | neutrophil activation | 1 | |
GO:0042176 | regulation of protein catabolic process | 1 | |
GO:0042246 | tissue regeneration | 1 | |
GO:0042307 | positive regulation of protein import into nucleus | 1 | |
GO:0042327 | positive regulation of phosphorylation | 1 | |
GO:0042542 | response to hydrogen peroxide | 1 | |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 1 | |
GO:0042692 | muscle cell differentiation | 1 | |
GO:0042742 | defense response to bacterium | 1 | |
GO:0042745 | circadian sleep/wake cycle | 1 | |
GO:0042770 | signal transduction in response to DNA damage | 1 | |
GO:0043086 | negative regulation of catalytic activity | 1 | |
GO:0043101 | purine-containing compound salvage | 1 | |
GO:0043103 | hypoxanthine salvage | 1 | |
GO:0043122 | regulation of I-kappaB kinase/NF-kappaB cascade | 1 | |
GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB cascade | 1 | |
GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | 1 | |
GO:0043171 | peptide catabolic process | 1 | |
GO:0043254 | regulation of protein complex assembly | 1 | |
GO:0043297 | apical junction assembly | 1 | |
GO:0043407 | negative regulation of MAP kinase activity | 1 | |
GO:0043408 | regulation of MAPK cascade | 1 | |
GO:0043456 | regulation of pentose-phosphate shunt | 1 | |
GO:0043462 | regulation of ATPase activity | 1 | |
GO:0043484 | regulation of RNA splicing | 1 | |
GO:0043488 | regulation of mRNA stability | 1 | |
GO:0043525 | positive regulation of neuron apoptotic process | 1 | |
GO:0043627 | response to estrogen stimulus | 1 | |
GO:0043966 | histone H3 acetylation | 1 | |
GO:0043967 | histone H4 acetylation | 1 | |
GO:0044319 | wound healing, spreading of cells | 1 | |
GO:0044772 | mitotic cell cycle phase transition | 1 | |
GO:0044803 | multi-organism membrane organization | 1 | |
GO:0045104 | intermediate filament cytoskeleton organization | 1 | |
GO:0045175 | basal protein localization | 1 | |
GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity | 1 | |
GO:0045199 | maintenance of epithelial cell apical/basal polarity | 1 | |
GO:0045214 | sarcomere organization | 1 | |
GO:0045216 | cell-cell junction organization | 1 | |
GO:0045429 | positive regulation of nitric oxide biosynthetic process | 1 | |
GO:0045454 | cell redox homeostasis | 1 | |
GO:0045597 | positive regulation of cell differentiation | 1 | |
GO:0045648 | positive regulation of erythrocyte differentiation | 1 | |
GO:0045653 | negative regulation of megakaryocyte differentiation | 1 | |
GO:0045724 | positive regulation of flagellum assembly | 1 | |
GO:0045730 | respiratory burst | 1 | |
GO:0045742 | positive regulation of epidermal growth factor receptor signaling pathway | 1 | |
GO:0045814 | negative regulation of gene expression, epigenetic | 1 | |
GO:0045815 | positive regulation of gene expression, epigenetic | 1 | |
GO:0045859 | regulation of protein kinase activity | 1 | |
GO:0045861 | negative regulation of proteolysis | 1 | |
GO:0045954 | positive regulation of natural killer cell mediated cytotoxicity | 1 | |
GO:0045995 | regulation of embryonic development | 1 | |
GO:0046103 | inosine biosynthetic process | 1 | |
GO:0046209 | nitric oxide metabolic process | 1 | |
GO:0046330 | positive regulation of JNK cascade | 1 | |
GO:0046426 | negative regulation of JAK-STAT cascade | 1 | |
GO:0046596 | regulation of viral entry into host cell | 1 | |
GO:0046627 | negative regulation of insulin receptor signaling pathway | 1 | |
GO:0046755 | non-lytic virus budding | 1 | |
GO:0046786 | viral replication complex formation and maintenance | 1 | |
GO:0046788 | egress of virus within host cell | 1 | |
GO:0046854 | phosphatidylinositol phosphorylation | 1 | |
GO:0046950 | cellular ketone body metabolic process | 1 | |
GO:0046951 | ketone body biosynthetic process | 1 | |
GO:0046952 | ketone body catabolic process | 1 | |
GO:0048167 | regulation of synaptic plasticity | 1 | |
GO:0048193 | Golgi vesicle transport | 1 | |
GO:0048488 | synaptic vesicle endocytosis | 1 | |
GO:0048524 | positive regulation of viral reproduction | 1 | |
GO:0048709 | oligodendrocyte differentiation | 1 | |
GO:0048806 | genitalia development | 1 | |
GO:0048839 | inner ear development | 1 | |
GO:0050714 | positive regulation of protein secretion | 1 | |
GO:0050727 | regulation of inflammatory response | 1 | |
GO:0050728 | negative regulation of inflammatory response | 1 | |
GO:0050732 | negative regulation of peptidyl-tyrosine phosphorylation | 1 | |
GO:0050770 | regulation of axonogenesis | 1 | |
GO:0050790 | regulation of catalytic activity | 1 | |
GO:0050830 | defense response to Gram-positive bacterium | 1 | |
GO:0050859 | negative regulation of B cell receptor signaling pathway | 1 | |
GO:0050863 | regulation of T cell activation | 1 | |
GO:0050868 | negative regulation of T cell activation | 1 | |
GO:0050890 | cognition | 1 | |
GO:0050904 | diapedesis | 1 | |
GO:0050999 | regulation of nitric-oxide synthase activity | 1 | |
GO:0051044 | positive regulation of membrane protein ectodomain proteolysis | 1 | |
GO:0051088 | PMA-inducible membrane protein ectodomain proteolysis | 1 | |
GO:0051091 | positive regulation of sequence-specific DNA binding transcription factor activity | 1 | |
GO:0051149 | positive regulation of muscle cell differentiation | 1 | |
GO:0051209 | release of sequestered calcium ion into cytosol | 1 | |
GO:0051279 | regulation of release of sequestered calcium ion into cytosol | 1 | |
GO:0051301 | cell division | 1 | |
GO:0051343 | positive regulation of cyclic-nucleotide phosphodiesterase activity | 1 | |
GO:0051384 | response to glucocorticoid stimulus | 1 | |
GO:0051402 | neuron apoptotic process | 1 | |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1 | |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1 | |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1 | |
GO:0051445 | regulation of meiotic cell cycle | 1 | |
GO:0051490 | negative regulation of filopodium assembly | 1 | |
GO:0051549 | positive regulation of keratinocyte migration | 1 | |
GO:0051893 | regulation of focal adhesion assembly | 1 | |
GO:0055117 | regulation of cardiac muscle contraction | 1 | |
GO:0055119 | relaxation of cardiac muscle | 1 | |
GO:0060048 | cardiac muscle contraction | 1 | |
GO:0060169 | negative regulation of adenosine receptor signaling pathway | 1 | |
GO:0060315 | negative regulation of ryanodine-sensitive calcium-release channel activity | 1 | |
GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity | 1 | |
GO:0060325 | face morphogenesis | 1 | |
GO:0060326 | cell chemotaxis | 1 | |
GO:0060334 | regulation of interferon-gamma-mediated signaling pathway | 1 | |
GO:0060337 | type I interferon-mediated signaling pathway | 1 | |
GO:0060338 | regulation of type I interferon-mediated signaling pathway | 1 | |
GO:0060546 | negative regulation of necroptosis | 1 | |
GO:0060547 | negative regulation of necrotic cell death | 1 | |
GO:0060612 | adipose tissue development | 1 | |
GO:0061001 | regulation of dendritic spine morphogenesis | 1 | |
GO:0061077 | chaperone-mediated protein folding | 1 | |
GO:0061084 | negative regulation of protein refolding | 1 | |
GO:0070228 | regulation of lymphocyte apoptotic process | 1 | |
GO:0070301 | cellular response to hydrogen peroxide | 1 | |
GO:0070371 | ERK1 and ERK2 cascade | 1 | |
GO:0070374 | positive regulation of ERK1 and ERK2 cascade | 1 | |
GO:0070389 | chaperone cofactor-dependent protein refolding | 1 | |
GO:0070433 | negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway | 1 | |
GO:0070498 | interleukin-1-mediated signaling pathway | 1 | |
GO:0070507 | regulation of microtubule cytoskeleton organization | 1 | |
GO:0070830 | tight junction assembly | 1 | |
GO:0070935 | 3'-UTR-mediated mRNA stabilization | 1 | |
GO:0071156 | regulation of cell cycle arrest | 1 | |
GO:0071225 | cellular response to muramyl dipeptide | 1 | |
GO:0071260 | cellular response to mechanical stimulus | 1 | |
GO:0071268 | homocysteine biosynthetic process | 1 | |
GO:0071300 | cellular response to retinoic acid | 1 | |
GO:0071346 | cellular response to interferon-gamma | 1 | |
GO:0071353 | cellular response to interleukin-4 | 1 | |
GO:0071372 | cellular response to follicle-stimulating hormone stimulus | 1 | |
GO:0071375 | cellular response to peptide hormone stimulus | 1 | |
GO:0071420 | cellular response to histamine | 1 | |
GO:0071447 | cellular response to hydroperoxide | 1 | |
GO:0071474 | cellular hyperosmotic response | 1 | |
GO:0071479 | cellular response to ionizing radiation | 1 | |
GO:0072011 | glomerular endothelium development | 1 | |
GO:0072657 | protein localization to membrane | 1 | |
GO:0072659 | protein localization to plasma membrane | 1 | |
GO:0075525 | viral translational termination-reinitiation | 1 | |
GO:0086002 | regulation of cardiac muscle cell action potential involved in contraction | 1 | |
GO:0086009 | membrane repolarization | 1 | |
GO:0086013 | membrane repolarization involved in regulation of cardiac muscle cell action potential | 1 | |
GO:0090084 | negative regulation of inclusion body assembly | 1 | |
GO:0090162 | establishment of epithelial cell polarity | 1 | |
GO:0090166 | Golgi disassembly | 1 | |
GO:0090312 | positive regulation of protein deacetylation | 1 | |
GO:0090331 | negative regulation of platelet aggregation | 1 | |
GO:0090398 | cellular senescence | 1 | |
GO:0090400 | stress-induced premature senescence | 1 | |
GO:0090557 | establishment of endothelial intestinal barrier | 1 | |
GO:0097155 | fasciculation of sensory neuron axon | 1 | |
GO:0097156 | fasciculation of motor neuron axon | 1 | |
GO:0097190 | apoptotic signaling pathway | 1 | |
GO:0097201 | negative regulation of transcription from RNA polymerase II promoter in response to stress | 1 | |
GO:0097352 | autophagic vacuole maturation | 1 | |
GO:0097435 | fibril organization | 1 | |
GO:0097485 | neuron projection guidance | 1 | |
GO:0098586 | cellular response to virus | 1 | |
GO:1900015 | regulation of cytokine production involved in inflammatory response | 1 | |
GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading | 1 | |
GO:1900121 | negative regulation of receptor binding | 1 | |
GO:1900126 | negative regulation of hyaluronan biosynthetic process | 1 | |
GO:1900163 | positive regulation of phospholipid scramblase activity | 1 | |
GO:1900182 | positive regulation of protein localization to nucleus | 1 | |
GO:1901215 | negative regulation of neuron death | 1 | |
GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction | 1 | |
GO:1902042 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | 1 | |
GO:1902188 | positive regulation of viral release from host cell | 1 | |
GO:1902219 | negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress | 1 | |
GO:1902254 | negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator | 1 | |
GO:1902570 | protein localization to nucleolus | 1 | |
GO:1903364 | positive regulation of cellular protein catabolic process | 1 | |
GO:1903421 | regulation of synaptic vesicle recycling | 1 | |
GO:1903551 | regulation of extracellular vesicular exosome assembly | 1 | |
GO:1903553 | positive regulation of extracellular vesicular exosome assembly | 1 | |
GO:1903772 | regulation of viral budding via host ESCRT complex | 1 | |
GO:1903774 | positive regulation of viral budding via host ESCRT complex | 1 | |
GO:1903861 | positive regulation of dendrite extension | 1 | |
GO:1904385 | cellular response to angiotensin | 1 | |
GO:1904715 | negative regulation of chaperone-mediated autophagy | 1 | |
GO:1904837 | beta-catenin-TCF complex assembly | 1 | |
GO:1904851 | positive regulation of establishment of protein localization to telomere | 1 | |
GO:1904871 | positive regulation of protein localization to Cajal body | 1 | |
GO:1904874 | positive regulation of telomerase RNA localization to Cajal body | 1 | |
GO:1905581 | positive regulation of low-density lipoprotein particle clearance | 1 | |
GO:1905597 | positive regulation of low-density lipoprotein particle receptor binding | 1 | |
GO:1905599 | positive regulation of low-density lipoprotein receptor activity | 1 | |
GO:1905602 | positive regulation of receptor-mediated endocytosis involved in cholesterol transport | 1 | |
GO:1990573 | potassium ion import across plasma membrane | 1 | |
GO:2000010 | positive regulation of protein localization to cell surface | 1 | |
GO:2000145 | regulation of cell motility | 1 | |
GO:2000146 | negative regulation of cell motility | 1 | |
GO:2000251 | positive regulation of actin cytoskeleton reorganization | 1 | |
GO:2000273 | positive regulation of receptor activity | 1 | |
GO:2000304 | positive regulation of ceramide biosynthetic process | 1 | |
GO:2000379 | positive regulation of reactive oxygen species metabolic process | 1 | |
GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation | 1 | |
GO:2000753 | positive regulation of glucosylceramide catabolic process | 1 | |
GO:2000755 | positive regulation of sphingomyelin catabolic process | 1 | |
GO:2001022 | positive regulation of response to DNA damage stimulus | 1 | |
GO:2001184 | positive regulation of interleukin-12 secretion | 1 | |
GO:2001275 | positive regulation of glucose import in response to insulin stimulus | 1 |