Homeodomain-interacting protein kinase 3

Site	Peptide	Modification	Experiment
Y8	MASQVLVyPPYVYQT	Phosphotyrosine	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphositePlus November 2016 PhosphoSite Plus Datasets, January 9, 2015 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSitePlus Datasets Combined June 2016 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined December 3, 2012
K27	FCSVKKLkVEPSSCV	Sumoylation	PhosphositePlus November 2016
K58	GNSHPPTkGSAFQTK	Ubiquitination	PhosphositePlus November 2016
Q142	DNHSSAMqIVDELSI	None	All human mutations dbSNP All mutations
T156	ILPAMLQtNMGNPVT	Phosphothreonine	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphositePlus November 2016 PhosphoSite Plus Datasets, January 9, 2015 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSitePlus Datasets Combined June 2016 PhosphoSite Plus Datasets Combined January 10, 2014
G170	TVVTATTgSKQNCTT	None	All human mutations dbSNP All mutations
C191	LVQHEVLcSMKNTYE	None	All human mutations dbSNP All mutations
T219	VKCWKRGtNEIVAIK	Phosphothreonine	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphositePlus November 2016 PhosphoSite Plus Datasets, January 9, 2015 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSitePlus Datasets Combined June 2016 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined December 3, 2012
S357	HVSKTVCsTYLQSRY	Phosphoserine	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets Combined July 11, 2014 PhosphositePlus November 2016 PhosphoSite Plus Datasets, January 9, 2015 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSitePlus Datasets Combined June 2016 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined December 3, 2012
T358	VSKTVCStYLQSRYY	Phosphothreonine	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets Combined July 11, 2014 Phosphosite, September 2009 B PhosphositePlus November 2016 PhosphoSite Plus Datasets, January 9, 2015 Phosphosite Plus Datasets Combined July 3, 2013 Phosphosite, September 2009 PhosphoSitePlus Datasets Combined June 2016 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined December 3, 2012
Y359	SKTVCSTyLQSRYYR	Phosphotyrosine	Flpin_EGFR_repB UniProtKB KMN UniprotKB - MOD_RES UniprotKB MOD_RES Dec. 16, 2016 Flpin_EGFR_repC [Samples with poor pre-treatment normalization removed] MEK-Dependent Negative Feedback Underlies BCR-ABL-Mediated Oncogene Addiction Phosphosite, September 2009 March 24 test Proteogenomics connects somatic mutations to signalling in breast cancer Waziri GBM Samples Phosphosite Plus Datasets Combined December 3, 2012 [Cell lines specified] Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer, with cell lines specified Guolin_H4006ER Flpin_EGFR PhosphoSitePlus Datasets Combined June 15, 2015 UniProtKB - MOD_RES dbPTM 3.0 experimentally verified PTM sites Phosphosite, September 2009 B PhosphoSite Plus Datasets, January 9, 2015 Phosphosite, September 2009 HPRD: Human Protein Reference Database Curated Modifications PhosphoSite, May 2007 UniProtKB - MOD_RES Ultra-deep tyrosine phosphoproteomics enabled by a phosphotyrosine superbinder Flpin_EGFR UniProtKB - MOD_RES Phospho.ELM v9.0 PhosphoSite Plus Datasets Combined July 11, 2014 PhosphositePlus November 2016 MEK-Dependent Negative Feedback Underlies BCR-ABL-Mediated Oncogene Addiction Synthesizing Signaling Pathways from Temporal Phosphoproteomic Data PhosphoSitePlus Datasets Combined June 2016 UniProtKB - MOD_RES Global Survey of Phosphotyrosine Signaling Identifies Oncogenic Kinases in Lung Cancer UniProtKB - MOD_RES Phosphorylation site dynamics of early T-cell receptor signaling Signaling networks assembled by oncogenic EGFR and c-MET: Profiling of lung cancer cell lines Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants Phosphosite Plus Datasets Combined July 3, 2013 MCF10A_ETP Akt-RSK-S6 kinase signaling networks activated by oncogenic receptor tyrosine kinases PhosphoSite Plus Datasets Combined January 10, 2014
Y359	SKTVCSTyLQSRYYR	None	Tinti All Peptides
S362	VCSTYLQsRYYRAPE	Phosphoserine	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets Combined July 11, 2014 dbPTM 3.0 experimentally verified PTM sites Phosphosite, September 2009 B PhosphositePlus November 2016 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015 Phosphosite, September 2009 PhosphoSitePlus Datasets Combined June 2016 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined December 3, 2012
K428	QLLNVGTkSTRFFCK	Ubiquitination	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets Combined July 11, 2014 dbPTM 3.0 experimentally verified PTM sites PhosphositePlus November 2016 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined December 3, 2012
K459	HEAETGMkSKEARKY	Ubiquitination	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets Combined July 11, 2014 dbPTM 3.0 experimentally verified PTM sites PhosphositePlus November 2016 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined December 3, 2012
Y466	KSKEARKyIFNSLDD	Phosphotyrosine	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphositePlus November 2016 PhosphoSite Plus Datasets, January 9, 2015 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSitePlus Datasets Combined June 2016 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined December 3, 2012
V474	IFNSLDDvAHVNTVM	None	All human mutations dbSNP All mutations
S500	ADRREFVsLLKKMLL	None	All human mutations dbSNP All mutations
T515	IDADLRItPAETLNH	Phosphothreonine	PhosphoSitePlus Datasets Combined June 2016
T519	LRITPAEtLNHPFVN	Phosphothreonine	PhosphoSitePlus Datasets Combined June 2016
K528	NHPFVNMkHLLDFPH	Methylation	PhosphositePlus November 2016
P729	NHYNSVMpQPLLTNQ	None	All human mutations dbSNP All mutations
S1205	AYTGFPLsPTKLSQY	Phosphoserine	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphositePlus November 2016 PhosphoSite Plus Datasets, January 9, 2015 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSitePlus Datasets Combined June 2016 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined December 3, 2012