E3 ubiquitin-protein ligase SHPRH

Site	Peptide	Modification	Experiment
S37	RNEPIIIsDDDEQPC	Phosphoserine	PhosphositePlus November 2016 PhosphoSite Plus Datasets Combined July 11, 2014 PhosphoSitePlus Datasets Combined June 2016 dbPTM 3.0 experimentally verified PTM sites PhosphoSitePlus Datasets Combined June 15, 2015 Phosphosite Plus Datasets Combined December 3, 2012 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined July 3, 2013 Proteogenomics connects somatic mutations to signalling in breast cancer PhosphoSite Plus Datasets, January 9, 2015
S78	KRCSKVVsFSKPIEK	Phosphoserine	PhosphositePlus November 2016 PhosphoSite Plus Datasets Combined July 11, 2014 PhosphoSitePlus Datasets Combined June 2016 PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets, January 9, 2015
S93	EETVGIFsPLSVKLN	Phosphoserine	PhosphoSitePlus Datasets Combined June 2016 PhosphositePlus November 2016 dbPTM 3.0 experimentally verified PTM sites
S266	EDEDDPEsEPEGQDI	Phosphoserine	PhosphoSite Plus Datasets Combined July 11, 2014 PhosphoSitePlus Datasets Combined June 2016 PhosphoSite Plus Datasets Combined January 10, 2014 UniProtKB - MOD_RES UniProtKB - MOD_RES UniProtKB - MOD_RES Phosphosite, September 2009 B Phosphosite Plus Datasets Combined December 3, 2012 Phosphosite Plus Datasets Combined July 3, 2013 UniProtKB KMN dbPTM 3.0 experimentally verified PTM sites PhosphoSitePlus Datasets Combined June 15, 2015 Phosphosite, September 2009 UniprotKB MOD_RES Dec. 16, 2016 UniProtKB - MOD_RES Phosphosite, September 2009 March 24 PhosphositePlus November 2016 UniprotKB - MOD_RES UniProtKB - MOD_RES PhosphoSite Plus Datasets, January 9, 2015 UniProtKB - MOD_RES
Y277	GQDIDELyHFVKQTH	Phosphotyrosine	PhosphositePlus November 2016 PhosphoSite Plus Datasets Combined July 11, 2014 PhosphoSitePlus Datasets Combined June 2016 PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015
Y351	LKLYYNPyTGCIIRE	Phosphotyrosine	PhosphoSitePlus Datasets Combined June 2016 Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels
T352	KLYYNPYtGCIIREY	Phosphothreonine	PhosphoSitePlus Datasets Combined June 2016 Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels
K379	ADEMGLGkTVEVLAL	N6-acetyllysine	PhosphositePlus November 2016 PhosphoSitePlus Datasets Combined June 15, 2015 acK test Phosphosite Plus Datasets Combined December 3, 2012 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015
K423	YFGGKLKkTEIQNIE	Sumoylation	PhosphositePlus November 2016
Q438	FEPKEKVqCPPTRVM	None	All human mutations dbSNP All mutations
S460	MNGKKGVsILSIYKY	None	All human mutations dbSNP All mutations
S470	SIYKYVSsIYRYDVQ	Phosphoserine	Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer. TCGA PNNL: Ovarian phosphoproteomic data
Y472	YKYVSSIyRYDVQRN	Phosphotyrosine	Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer. TCGA PNNL: Ovarian phosphoproteomic data TCGA PNNL: Ovarian phosphoproteomic data phosphotyrosine subset
Y474	YVSSIYRyDVQRNRS	Phosphotyrosine	Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer. TCGA PNNL: Ovarian phosphoproteomic data TCGA PNNL: Ovarian phosphoproteomic data phosphotyrosine subset
S481	YDVQRNRsLLKRMLK	Phosphoserine	Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels
S530	TKKQAVGsPRKIQKE	Phosphoserine	PhosphoSitePlus Datasets Combined June 2016 Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels
Y563	SDDDDDPyYYYYKSR	None	Tinti All Peptides
S597	QPFINPDsQGHCPAT	Phosphoserine	PhosphositePlus November 2016 PhosphoSite Plus Datasets Combined July 11, 2014 Phosphosite, September 2009 B dbPTM 3.0 experimentally verified PTM sites PhosphoSitePlus Datasets Combined June 2016 PhosphoSitePlus Datasets Combined June 15, 2015 Phosphosite, September 2009 Phosphosite Plus Datasets Combined December 3, 2012 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015 Phosphosite, September 2009 March 24
S635	ETEDCAEsLNHADSD	Phosphoserine	UniprotKB - MOD_RES UniprotKB MOD_RES Dec. 16, 2016
Y691	QHAKCVNyDEKNLKI	Phosphotyrosine	PhosphositePlus November 2016 PhosphoSitePlus Datasets Combined June 2016 PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015
S787	NYVDIPHsNSEDGRR	Phosphoserine	PhosphoSitePlus Datasets Combined June 2016 PhosphositePlus November 2016 PhosphoSite Plus Datasets, January 9, 2015 PhosphoSitePlus Datasets Combined June 15, 2015
S789	VDIPHSNsEDGRRLR	Phosphoserine	PhosphoSitePlus Datasets Combined June 2016 PhosphositePlus November 2016 PhosphoSite Plus Datasets, January 9, 2015 PhosphoSitePlus Datasets Combined June 15, 2015
Y801	RLRNQKRyMAIPSPL	Phosphotyrosine	[Cell lines specified] Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer, with cell lines specified PhosphoSite Plus Datasets Combined July 11, 2014 Phosphosite, September 2009 B dbPTM 3.0 experimentally verified PTM sites PhosphoSitePlus Datasets Combined June 15, 2015 Phosphosite, September 2009 Phosphosite Plus Datasets Combined December 3, 2012 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015 Phosphosite, September 2009 March 24
S839	AEMAQRLsGINRWCI	Phosphoserine	PhosphositePlus November 2016 PhosphoSitePlus Datasets Combined June 2016 PhosphoSitePlus Datasets Combined June 15, 2015 Phosphosite Plus Datasets Combined December 3, 2012 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015
Y934	SPVERHFyHRQHEVC	Phosphotyrosine	[Cell lines specified] Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer, with cell lines specified PhosphoSite Plus Datasets Combined July 11, 2014 Phosphosite, September 2009 B dbPTM 3.0 experimentally verified PTM sites PhosphoSitePlus Datasets Combined June 15, 2015 Phosphosite, September 2009 Phosphosite Plus Datasets Combined December 3, 2012 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015 Phosphosite, September 2009 March 24
K951	DVVVKLRkISDWALK	N6,N6-dimethyllysine	PhosphositePlus November 2016 PhosphoSitePlus Datasets Combined June 15, 2015 Phosphosite Plus Datasets Combined December 3, 2012 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015
Y972	RTVTSILyPLLRLRQ	Phosphotyrosine	PhosphositePlus November 2016 PhosphoSitePlus Datasets Combined June 2016 PhosphoSitePlus Datasets Combined June 15, 2015 Phosphosite Plus Datasets Combined December 3, 2012 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015
N1028	RQLVCALnGLAGIHI	None	All human mutations dbSNP All mutations
K1176	NYKQQTGkLSMSEKF	N6-acetyllysine	PhosphositePlus November 2016 PhosphoSitePlus Datasets Combined June 15, 2015 acK test Phosphosite Plus Datasets Combined December 3, 2012 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015
V1222	EGPPSRNvIESATVC	None	All human mutations dbSNP All mutations
K1256	LFTEYESkLFSNTVK	Ubiquitination	PhosphositePlus November 2016 PhosphoSite Plus Datasets Combined July 11, 2014 dbPTM 3.0 experimentally verified PTM sites PhosphoSitePlus Datasets Combined June 15, 2015 Phosphosite Plus Datasets Combined December 3, 2012 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015
S1306	RSMKAILsFAKSHRF	Phosphoserine	PhosphositePlus November 2016 PhosphoSite Plus Datasets Combined July 11, 2014 PhosphoSitePlus Datasets Combined June 2016 PhosphoSitePlus Datasets Combined June 15, 2015 Phosphosite Plus Datasets Combined December 3, 2012 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015
S1310	AILSFAKsHRFDVEF	Phosphoserine	dbPTM 3.0 experimentally verified PTM sites
S1488	TTSHKEIsYVFTSEK	Phosphoserine	PhosphositePlus November 2016 PhosphoSitePlus Datasets Combined June 2016 PhosphoSitePlus Datasets Combined June 15, 2015 Phosphosite Plus Datasets Combined December 3, 2012 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015
S1493	EISYVFTsEKANQEE	Phosphoserine	PhosphositePlus November 2016 PhosphoSitePlus Datasets Combined June 2016 PhosphoSitePlus Datasets Combined June 15, 2015 Phosphosite Plus Datasets Combined December 3, 2012 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015
K1495	SYVFTSEkANQEEDI	N6-acetyllysine	PhosphositePlus November 2016 PhosphoSite Plus Datasets Combined July 11, 2014 dbPTM 3.0 experimentally verified PTM sites PhosphoSitePlus Datasets Combined June 15, 2015 acK test Phosphosite Plus Datasets Combined December 3, 2012 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015
K1562	FAQISRVkTFQENLS	Ubiquitination	PhosphositePlus November 2016 PhosphoSite Plus Datasets Combined July 11, 2014 dbPTM 3.0 experimentally verified PTM sites PhosphoSitePlus Datasets Combined June 15, 2015 Phosphosite Plus Datasets Combined December 3, 2012 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015
K1572	QENLSAFkRDPQINI	Ubiquitination	PhosphositePlus November 2016 PhosphoSite Plus Datasets Combined July 11, 2014 dbPTM 3.0 experimentally verified PTM sites PhosphoSitePlus Datasets Combined June 15, 2015 Phosphosite Plus Datasets Combined December 3, 2012 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015
T1676	ADLADLFtKETEELE	Phosphothreonine	PhosphositePlus November 2016 PhosphoSitePlus Datasets Combined June 2016 PhosphoSitePlus Datasets Combined June 15, 2015 Phosphosite Plus Datasets Combined December 3, 2012 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined July 3, 2013 PhosphoSite Plus Datasets, January 9, 2015