[Samples with poor pre-treatment normalization removed] MEK-Dependent Negative Feedback Underlies BCR-ABL-Mediated Oncogene Addiction
- Experiment Name
- [Samples with poor pre-treatment normalization removed] MEK-Dependent Negative Feedback Underlies BCR-ABL-Mediated Oncogene Addiction
- Citation
- Asmussen J,Lasater EA,Tajon C,Oses-Prieto J,Jun YW,Taylor BS,Burlingame A,Craik CS,Shah NP. Cancer discovery. 2014-February. Vol 4. 200-15. [pubmed]
- Description
- Quantitative measurements of phosphotyrosine dynamics in K562 cells (patient-derived CML cell line) treated with a high dose of dasatinib (100nmol/L). Measurements taking before treatment, at washout (EOE), and 3 and 6 hours post-treatment (all treatments were for 20minutes). -- Those samples that had issues with the pre-treatment normalizations were removed in this extension.
- Conditions
-
- Cell
- K562
- Drug
- Dasatinib
- Date Loaded
- April 07 2016
Tools
- Experiment Summary
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